This is the same enzyme discussed above under ALT. It is important enough in current-affairs/health questions to remember its biochemical identity.

Key Pointers

  • Category: Science & Health
  • Abbreviation: ALT
  • Older/common clinical term: SGPT.
  • Catalyses transfer of an amino group between amino acids and keto acids.
  • Important in amino-acid metabolism.
  • High serum levels may indicate hepatocellular injury.
  • ALT is generally more liver-specific than AST, although interpretation requires clinical context.

Prelims Focus: ALT/SGPT → liver enzyme → amino-acid metabolism.