Alanine aminotransferase (ALT) is an enzyme found predominantly in the liver. It plays a role in amino-acid metabolism.

Measurement of ALT in blood is commonly used as an indicator of liver-cell injury.

Key Pointers

  • Category: Science & Health
  • Full form: Alanine aminotransferase
  • Formerly also called SGPT.
  • Predominantly associated with liver tissue.
  • Elevated ALT may indicate liver-cell injury.
  • Possible causes include:
    • Viral hepatitis
    • Fatty liver disease
    • Certain drugs/toxins
    • Alcohol-related liver injury
  • ALT alone does not establish a specific diagnosis.

Prelims Focus: ALT = SGPT → important liver enzyme.