Sepsis is a life-threatening condition caused by a dysregulated response of the body to infection, leading to organ dysfunction.

It is a major global public-health concern.

Key Pointers

  • Category: Science & Health
  • Trigger: Infection.
  • Problem: Dysregulated host response.
  • Can cause:
    • Organ dysfunction
    • Circulatory abnormalities
    • Tissue damage
  • Common infection sources:
    • Lungs
    • Urinary tract
    • Abdomen
    • Bloodstream
  • Septic shock is a severe subset of sepsis associated with profound circulatory and metabolic abnormalities.
  • Early recognition and treatment are critical.

Prelims Focus: Infection → dysregulated response → organ dysfunction.